Assessment (in vitro) toxicity of small molecules of plant origin

Small molecules of plant origin can have different effects on bacterial cells. At present, it is great interest to determine the toxic such compounds in order assess potential their use veterinary medicine and medicine. The aim this work was evaluate toxicity various chemically synthesized small using a luminescent biosensor based Escherichia coli cell culture freshwater ciliate Stylonychia mytilus . Cinnamic aldehyde had greatest effect E. MG1655 pXen7 lux -biosensor, which expressed significant decrease luminescence level strain compared control. Quercetin concentration range used did not affect intensity -biosensor. Coumarin vanillin were characterized by similar manifestation effect. Similar results also confirmed S. as test object. obtained expand understanding possible phytochemicals, be development feed additives animal husbandry (as analogues antibiotics).